Cisplatin discovery
WebCisplatin 9. The Discovery - One Scientist's Story ChemCases Kennesaw State University References As we saw in the role of platinum electrodes module, the researchers found that certain transition metal complexes—specifically, soluble metal salts—caused elongation of E. coli bacterial cells. WebThe discoverers of cisplatin observed an unexpected cell phenomenon, then they evaluated what they saw and came to an exciting hypothesis that something was changing cell behavior in a way that might be useful …
Cisplatin discovery
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WebCisplatin 9. The Discovery - One Scientist's Story ChemCases Kennesaw State University References As we saw in the role of platinum electrodes module, the researchers found … WebJan 1, 1980 · INTRODUCTION. Cisplatin ( cis -dichlorodiammineplatinum II) is the first member of a new class of potent anticancer drugs, the metal coordination complexes, to enter general use in cancer chemotherapy. This represents a reintroduction into medicine of such metal complexes in recent times.
WebNational Center for Biotechnology Information WebNov 23, 2024 · Since its discovery, cisplatin has become the key drug in chemotherapy for cancers. Nevertheless, chemoresistance in cancers has become an impediment in using cisplatin for cancer treatment. The resistance toward cisplatin is multifaceted as it involves multiple cellular pathways. Ever since the knowledge of long noncoding RNAs as …
WebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is often … WebThe accidental discovery of the anticancer properties of cisplatin and its clinical introduction in the 1970s represent a major landmark in the history of successful anticancer drugs. Although carboplatin--a second-generation analogue that is safer but shows a similar spectrum of activity to cisplat …
WebOct 5, 2014 · Cisplatin is cleared by the kidney by both glomerular filtration and tubular secretion (Yao, Panichpisal et al., 2007; Ishida, Lee et al., 2002) Cisplatin concentrations …
WebSep 15, 2024 · Pd(II)-compounds are presently regarded as promising anticancer drugs, as an alternative to Pt(II)-based drugs (e.g., cisplatin), which typically trigger severe side-effects and acquired resistance. Dinuclear Pd(II) complexes with biogenic polyamines such as spermine (Pd 2 Spm) have exhibited particularly beneficial cytotoxic properties, hence ... norse god of technologyWebIn the modules on control experiments and the role of platinum electrodes (as well as the discovery of cisplatin), we saw that platinum-containing electrolysis products were responsible for causing both elongation of bacterial cells and regression of murine tumors. We now discuss the origin of these electrolysis products. norse god of travelWebMar 24, 2005 · Cisplatin is a platinum-based drug that has been in widespread use for many years to treat several forms of cancer, including testicular, ovarian, cervical, head and neck, and non-small-cell lung ... norse god of the windWebCisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar platinum -based drugs were developed with … Cisplatin is approved to be used alone or with other drugs to treat: Bladder … norse god of the oceanhow to rename screen in linuxWebSep 30, 2024 · In 1978, it was approved by the US Food and Drug Administration (FDA) as an anticancer treatment for patients with testicular and bladder cancer. Since then, … how to rename scottybotWebCisplatin or (SP-4-2)-diamminedichloridoplatinum(II) is one of the most potential and widely used drugs for the treatment of various solid cancers such as testicular, ovarian, head and neck, bladder, lung, cervical cancer, melanoma, lymphomas and several others. Cisplatin exerts anticancer activity … Cisplatin: The first metal based anticancer drug how to rename several files at once