Human autoantigen database

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Web1 Jan 2024 · Autoantibodies are antibodies against host self-proteins (autoantigens), which play significant roles in homeostasis maintenance and diseases with autoimmune disorders. Numerous papers were published in the past decade on the identification of human autoantigens in different human diseases. WebThe database is freely accessible at http://biokb.ncpsb.org/aagatlas/. We believe this database will be a valuable resource to track and understand human autoantigens as …

AAgAtlas 1.0: A human autoantigen database - Arizona …

WebAAgAtlas 1.0: a human autoantigen database Overview of attention for article published in Nucleic Acids Research, October 2016 Summary Blogs Twitter Dimensions citations You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more . WebTo address this need, previously we developed a human autoantigen database, AAgAtlas 1.0, by text-mining and manual curation, which collects 1126 autoantigens associated with 1071 human diseases. AAgAtlas 1.0 provides a user-friendly interface to conveniently browse, retrieve, and download human autoantigen genes, their functional annotation, … self owned business tax form

Autoantibody:Autoantigen Competitor Decoys: Application to …

Web27 Jan 2024 · Autoantibodies are produced to target an individual's own antigens (e.g. proteins). They can trigger autoimmune responses and inflammation, and thus, cause … WebAAgAtlas is an online database provided by National Center for Protein Science (Beijing); it contains a comprehensive list of human autoantigens with their correspondent evidences in literature, derived by text mining … Autoantibodies (AAb) are antibodies that bind to individual's own antigens. Their production can be affected by genetic predisposition, environment, viruses and pathogens (via epitope mimicking) and chemicals, etc. In the last three decades numerous studies have been devoted to elucidating the … See more Our data collection relied on the text mining of AAg-related PubMed abstracts. Bio-entity recognition and extraction from these abstracts for human AAg candidates were performed by our custom developed ontology-based bio … See more Since the first AAg paper appeared in 1945, more than 120 000 papers have been published and 1000 AAgs have been identified. Some of … See more We provide a user-friendly web interface that facilitates searching, exploring information and updating the AAgAtlas 1.0 database (http://biokb.ncpsb.org/aagatlas/) (Figure 4). The … See more AAgAtlas database runs entirely on open software (MySQL database server, Apache web server with the interface written in PHP, … See more self owned business ideas

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AAgAtlas 1.0: A human autoantigen database - ResearchGate

Web1 Jan 2024 · Autoantibodies are antibodies against host self-proteins (autoantigens), which play significant roles in homeostasis maintenance and diseases with autoimmune … WebExplore the Sengenics protein database and access the complete list of Sengenics proteins found on our best-in-class arrays. Services. ... ORVAR Autoantigen Discovery Platform; The Value of Autoantibodies; Bioinformatics for Autoantibodies; Resources. ... HUMAN Double-strand-break repair protein rad21 homolog: hHR21, KIAA0078, SCC1 ... self owned cars for saleWebFrom the ‘Home’ page, the users can see the introduction of AAgAtlas 1.0 database and search for the gene or disease of their interest. From the ‘Browse & Download’, the users … self owned business taxes

"Web12 Mar 2024 · Autoantibodies are antibodies against host self-proteins (autoantigens), which play significant roles in homeostasis maintenance and diseases with autoimmune … " - Human autoantigen database

Human autoantigen database

Detection of Posttranslational Modification Autoantibodies Using ...

Web19 Oct 2016 · Europe PMC is an archive of life sciences journal literature. Search life-sciences literature (Over 39 million (Over 39 million Web19 Aug 2024 · A human autoantigen database (AAgAtlas database 1.0) is constructed using text-mining and manual curation that provides a user-friendly interface to conveniently browse, retrieve and download humanAutoantigens as well as their associated diseases.

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Web28 Jan 2024 · This database reveals that intracellular nucleic acid binding proteins and signaling molecules are the most likely to behave as autoantigens. Indeed, the historical flagship Ro (SSA) and La (SSB) autoantigens are proteins in these classes. Web1 Jan 2024 · Autoantibodies are produced to target an individual's own antigens (e.g. proteins). They can trigger autoimmune responses and inflammation, and thus, cause many types of diseases. Many high-throughput autoantibody profiling projects have been reported for unbiased identification of serological autoantigen-based biomarkers.

Web1 May 2024 · Although autoimmunity and autoimmune disease (AID) are relatively common, the repertoire of autoantigens is paradoxically very limited. Highly enriched in this autoantigen repertoire are nucleic acids and their binding proteins, which together form large macromolecular structures. Web1 Jan 2024 · Human serum autoantigens are a great resource of generating non-invasive biomarkers with well-established detection methods in the clinics, including the ELISA …

WebNational Center for Biotechnology Information WebAs part of our investigations, we are releasing and maintaining this public database to document all published/patented antibodies and nanobodies able to bind to …

Web9 Feb 2000 · The autoantigens were shown to cluster in two discrete cell surface 'membrane blebs'. The larger blebs (called apoptotic bodies) contained predominantly Ro, La, snRNPs, and nucleosomal DNA. The smaller structures were recognized by autoantibodies specific for endoplasmic reticulum components, as well as Ro and ribosomal components [ 12 ].

Web1 Sep 2002 · Valenta et al. published a DNA sequence for an expressed human autoantigen named HOMS-1 (GenBank accession no. Y14314) with almost complete sequence identity to SART-1; this sequence is unlikely to represent the full-length cDNA, since it leaves out the first 38 amino acids compared with the Itoh et al. sequence. self owned businesses near meWeb12 May 2024 · A platform, Cancer Antigens Database (CAD, http://cad.bio-it.cn/), was designed to facilitate users to perform a complete exploration of cancer antigens online. … self ownership meaningWebHuman autoantigen database Description More detailed information about this field from each metasource. ×. Human autoantigen database ... MUGEN mouse database. The MUGEN mouse database (MMdb) is a database of murine models of immune processes and immunological diseases. self owned propertyWebMany autoantigens consist of RNA-binding proteins complexed with RNA molecules. These ribonucleoproteins are highly conserved, and many have microbial orthologs. There is increasing evidence that the microbiome plays an important role in the development of many autoimmune diseases. self owned meaningWebAAgAtlas 1.0 provides a user-friendly interface to conveniently browse, retrieve, and download human autoantigen genes, their functional annotation, related diseases, and … self ownership nozickWebAutoantibodies are antibodies against host self-proteins (autoantigens), which play significant roles in homeostasis maintenance and diseases with autoimmune disorders. … self owned homes for rentWeb19 Oct 2016 · The database is freely accessible at http://biokb.ncpsb.org/aagatlas/ We believe this database will be a valuable resource to track and understand human autoantigens as well as to investigate their functions in basic and translational research. Free full text Nucleic Acids Res. 2024 Jan 4; 45(Database issue): D769–D776. self ownership synonym